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Anti-inflammatory Drug May Improve Fibrosis

Learn about a medication for liver fibrosis.

Cenicriviroc, a drug that blocks both CCR5 and CCR2 receptors on immune cells, may be a potential treatment for liver fibrosis in people with severe fatty liver disease, according to the results of a Phase II study.

Published in the August 17 online edition of Hepatology, the study showed that while cenicriviroc did not decrease liver steatosis (fat accumulation) or liver inflammation in patients with non-alcoholic steatohepatitis (NASH), it did reduce liver fibrosis significantly more than a placebo did.

Fatty liver disease, often associated with obesity and metabolic syndrome, is a leading cause of liver problems in the United States. Non-alcoholic fatty liver disease (NAFLD) and its more severe form, NASH, refer to the buildup of fat in the liver in people who do not drink heavily. Over time, fat accumulation and the accompanying inflammation and buildup of scar tissue (fibrosis and cirrhosis) can interfere with normal liver function and lead to liver cancer. To date there are no good treatments for NAFLD, but several are under study.

Read full article: Anti-inflammatory Drug May Improve Fibrosis – Hep

Read Full Article: Anti-inflammatory Drug May Improve Fibrosis – Hep

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