The brain shrinkage seen in multiple sclerosis might be linked to protein leakage.
A leak of a protein called haemoglobin from damaged red blood cells may be associated with brain shrinkage in multiple sclerosis.
This is the conclusion of a team from Imperial College London, whose early-stage findings suggest treatments that lower levels of haemoglobin could slow progression of the disease. Haemoglobin carries iron and oxygen around the body in red blood cells.
The research, which involved 140 patients with an advanced form of the disease, called secondary progressive multiple sclerosis, has just passed peer review on new publishing platform, Wellcome Open Research.
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