The BRCA gene in young people does not mean that survival times are less.
Young breast cancer patients with faulty BRCA genes have the same survival chances as those without, a study has found.
The researchers, who looked at almost 3,000 women, also found outcomes were the same whatever kind of treatment women had – including mastectomies.
Experts say it means women can take time to decide if the radical surgery is right for them.
The study did not look at preventative mastectomies.
These are offered to women with faulty genes to cut their risk of developing cancer.
Mutations in the BRCA1 and BRCA2 genes increase a woman’s risk of breast cancer by four-to-eightfold and can explain why some families have lots of relatives diagnosed with breast cancer.
The study, published in The Lancet Oncology, found 12% of 2,733 women aged 18 to 40 treated for breast cancer at 127 hospitals across the UK between 2000 and 2008 had a BRCA mutation.
The women’s medical records were tracked for up to 10 years.
During this time, 651 of the women died from breast cancer, and those with the BRCA mutation were equally likely to have survived at the two-, five- and 10-year mark as those without the genetic mutation.
This was not affected by the women’s body mass index or ethnicity.
About a third of those with the BRCA mutation had a double mastectomy to remove both breasts after being diagnosed with cancer. This surgery did not appear to improve their chances of survival at the 10-year mark.
But the researchers said surgery may still be beneficial for these patients to reduce their risk of a new cancer developing in the longer term.
Read full article: Breast cancer survival ‘unaffected by faulty gene’ – BBC News
|Read Full Article: Breast cancer survival ‘unaffected by faulty gene’ – BBC News|