It appears that the death of certain brain cells could be a trigger for multiple sclerosis (MS).
One trigger for multiple sclerosis (MS) might the death of brain cells that make myelin, according to a study published in the journal Nature Neuroscience.
Researchers from the University of Chicago and Northwestern Medicine developed genetically engineered mice models in order to investigate whether cell death could cause this autoimmune response. The researchers used the mice to target the brain cells that make myelin, called oligodendrocytes. Then, the investigators killed the oligodendrocytes and observed the changes in the way the mice walked.
After the initial cell death, the central nervous system in the mice regenerated and the animals’ gait returned to normal. However, after 6 months, the MS like symptoms, including impaired walk, came back in the mice models.
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