The two common inflammatory bowel diseases (IBD) of celiac disease and Crohn’s disease share common symptoms and also appear to be part of the same genetic background.
Celiac disease and Crohn’s disease are two common inflammatory bowel diseases (IBD) that not only share common symptoms but also part of their genetic background. In both celiac disease and Crohn’s disease there is inflammation of the intestines but how that inflammation is triggered differs.
Celiac disease is intolerance to gluten and so when a person consumes gluten it creates an immune response which contributes to inflammation along with other symptoms. In Crohn’s disease is a disease which can occur at any part of the digestive system – from the mouth to the anus. Another autoimmune disease, an immune response is triggered which contributes to painful and uncomfortable symptoms.
Proper diagnosis is key in order to properly manage either condition and reduce flare-ups and live a normal life.
Previous research found that celiac disease and Crohn’s disease share part of their genetic background. Researchers combined meta-analysis of genome-wide data for both diseases where they found shared risk loci.
Although some aspects of celiac disease and Crohn’s disease are understood, there are still many questions which researchers are trying to uncover. Researchers do know that both genetic and environmental factors play a role in both diseases. Celiac disease is more common than Crohn’s disease and although celiac is known to be triggered by gluten, less is known about what exactly causes Crohn’s disease.