The highest rates of Crohn’s disease are found in states with high smoking rates.
According to a research study conducted at the Price Institute of Surgical Research, in Louisville, Kentucky, and published in the Journal of Clinical Gastroenterology, U.S. states that report the highest rates of Crohn’s disease (CD) also have high smoking rates.
For the study, the researchers incorporated a linear regression analysis of national data. After analyzing all the relevant data, the researchers concluded that there is a correlation between regionally high rates of smoking and the number of Crohn’s disease hospital discharges for that region. Before the study, the investigators had a theory, which was based on an established fact that compared to non-smoking CD patients, smoker CD patients have a 2.5-fold increased risk of surgical recurrence and twice the probability of disease relapse. The study proved that their theory was well founded.
U.S. states with high hospital discharges for Crohn’s disease: For the first part of the study, the researchers designed a population-based study and analyzed the Healthcare Cost and Utilization Project (HCUP) in order to have access to the discharge data on Crohn’s disease, ulcerative colitis, and lung cancer. The HCUP collects and stores patient discharge information from 30 U.S. states.
U.S. states with high smoker rates: For the next part of the study — finding the estimated smoking prevalence rates among adult residents in the same 30 states— the researchers analyzed data from the U.S. Centers for Disease Control and Prevention. West Virginia, Tennessee, Oklahoma, Kentucky, and Missouri are the states with the highest smoking rates, in which almost 25 percent of the adult population smokes. On the other hand New Jersey, Maryland, Utah, California, and Arizona, had the lowest percentage of smokers.
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