Crohn’s Disease Relapses Strongly Tied to Tobacco Smoking

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Crohn’s Disease Relapses Strongly Tied to Tobacco Smoking

Tobacco smoking makes disease relapses much more likely in patients with Crohn’s disease.

Disease relapses in patients with Crohn’s disease and smoking appear to be strongly linked, a study titled “Impact of Smoking Cessation on the Clinical Course of Crohn’s Disease Under Current Therapeutic Algorithms: A Multicenter Prospective Study” reported. The study was published in The American Journal of Gastroenterology.

According to the Crohn’s and Colitis Foundation of America, approximately 1.6 million Americans suffer from inflammatory bowel disease (IBD), with Crohn’s disease (CD) being one main type of IBD. Tobacco smoking is the only environmental factor repeatedly linked to the development of CD, but only a handful of prospective studies have actually investigated the link between tobacco smoking and an increased frequency of clinical relapses in CD patients.

“The present study is indeed the second trial to prospectively assess the effect of smoking cessation on CD relapse and the first study to do so in the biologic era,” the researchers wrote, according to a news release.

In this multicenter prospective cohort study, a total of 573 CD patients were analyzed. The patients were in clinical remission with diverse smoking habits, and were all encouraged to quit smoking. The team examined the impact of smoking in clinical relapses and the advantages of quitting.

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