People with a form of Crohn’s disease affecting the the lower part of the small intestine have a higher risk of relapse after surgery.
New research shows that more than 25% of patients with Crohn’s disease (CD) relapse after surgery, and those with ileal disease — inflammation and irritation of the ileum, the lower part of the small intestine — have more than a threefold higher risk of the disease recurring.
These results are from a review study titled “Systematic review with meta-analysis: recurrence of Crohn’s disease after total colectomy with permanent ileostomy,” published in the journal Alimentary Pharmacology and Therapeutics.
“Crohn’s disease patients who are having total colectomy and ileostomy have a low risk of recurrence,” Siddharth Singh, MD, of the division of gastroenterology at the University of California San Diego, said in a press release. “These patients should be monitored, and treatment started in case of recurrence. This is especially important for those patients who ever had Crohn’s disease involving the last part of the small intestine.”
Despite significant advances in the treatment of Crohn’s disease, almost half of patients require surgery within 10 years of their diagnosis, and about 30% require surgery at some point in their lifetime. But surgery rarely cures the disease, and most patients experience post-surgical disease recurrence.
Read full article: Crohn’s Ileal Disease Patients at Higher Risk of Relapse After Surgery
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