Health Specialists Safely Transplanted Hepatitis C infected Organs in Patients

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Health Specialists Safely Transplanted Hepatitis C infected Organs in Patients

Several health experts including surgeons, transplant physicians and infectious disease health specialists at Brigham and Women’s Hospital were successful in blocking the transmission of hepatitis C virus from infected organ donors to recipients who were in need of hearts or lungs.

Several health experts including surgeons, transplant physicians and infectious disease health specialists at Brigham and Women’s Hospital were successful in blocking the transmission of hepatitis C virus from infected organ donors to recipients who were in need of hearts or lungs.

The DONATE HCV Trial Team says that hepatitis C-infected thoracic organs can now also be securely transplanted, showing no signs and symptoms of the infection and great results for the transplanted organs in all patients. The patients were given a short course of antivirals to inhibit the growth of viruses.

The research paper is published in the New England Journal of Medicine. The study describes that patients were given antivirals for consecutive 4 weeks within the few hours of the transplantation. It helped in counteracting hepatitis C infection (HCV) contamination in all patients, and, in this manner, growing the pool of healthy heart and lung donor organs.

“There was a 100 percent success rate in terms of HCV treatment and six-month graft survival,” said study author Ann Woolley, MD, MPH, of the Department of Infectious Diseases at the Brigham.

“Direct-acting antivirals have revolutionized the field of hepatitis C treatment and have also created an opportunity to transplant organs from hepatitis C positive donors. While transplants from hepatitis C positive donors have previously been done, the best approach to doing this—when to initiate treatment and how long to treat patients after transplant—, as well as the outcomes for heart and lung transplant recipients, have not previously been systematically studied.”

“This is the largest clinical trial to date for HCV thoracic organ transplantation and provides clear evidence that this shortened regimen, initiated within hours of transplant, can prevent the establishment of hepatitis C in the recipients and lead to excellent outcomes for patients.”

Read on: Health Specialists Safely Transplanted Hepatitis C infected Organs in Patients

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