MS News that Caught My Eye: Remyelination, Predicting SPMS, Switching DMTs, MS and a Virus

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MS News that Caught My Eye: Remyelination, Predicting SPMS, Switching DMTs, MS and a Virus

Coverage of some of the latest research about multiple sclerosis.

A chemical compound called indazole chloride promotes repair of myelin, the protective layer of nerve fibers, through “beneficial” inflammation in a mouse model of multiple sclerosis (MS), a study reports.

The preclinical research, “Increase in chemokine CXCL1 by ERβ ligand treatment is a key mediator in promoting axon myelination,” was published in the journal Proceedings of the National Academy of Sciences.

Study Examines Factors That Increase Risk of Progressing from RRMS to SPMS

Many of us who begin our MS with the relapsing form of the disease eventually progress to secondary progressive. There hasn’t been a good method of predicting who will move from RRMS to SPMS, or when, but this study has discovered some “markers” that may provide a way to make that determination.

Age at disease onset, number of early relapses, and the extent of brain damage at baseline can help identify those who are at high risk of progression from relapsing-remitting multiple sclerosis into the secondary progressive phase of the disease, a new study shows.

The study with that finding, “The cortical damage, early relapses, and onset of the progressive phase in multiple sclerosis,” was published in the journal Neurology.

Read on: MS News that Caught My Eye: Remyelination, Predicting SPMS, Switching DMTs, MS and a Virus 

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