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Multiple Sclerosis Risk Linked to Malaria-resisting Gene Variation

A gene variation that helped in resisting malaria could increase the risk of multiple sclerosis.

A variation in a gene that likely promoted resistance to malaria in Sardinia may have increased the risk of people there developing autoimmune diseases such as multiple sclerosis (MS) and systemic lupus erythematosus (SLE).

The study, “Overexpression of the Cytokine BAFF and Autoimmunity Risk,” was published in The New England Journal of Medicine.

Autoimmune diseases are caused by still largely unknown environmental factors that affect some people more than others. This is because we all carry genome differences, so some of us are genetically more susceptible to the factors than others.

Researchers have done what are known as genome-wide association studies of autoimmune diseases to try to detect which genome variations are associated with particular diseases. They identified only a few genes that cause diseases, however. And they were unable to learn how most of the genes cause the diseases.

Read full article: Multiple Sclerosis Risk Linked to Malaria-resisting Gene Variation

Read Full Article: Multiple Sclerosis Risk Linked to Malaria-resisting Gene Variation

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