New treatments for Crohn’s disease are being researched.
A new discovery could lead to the development of treatments for Crohn’s disease and its debilitating complications.
In a study published in Science Immunology, scientists from the University of British Columbia (UBC) were able to prevent the development of fibrosis in laboratory mice after infecting them with a type of salmonella bacteria that mimics the symptoms of Crohn’s disease. According to the researchers, the mutation that prevented fibrosis had switched off a hormone receptor responsible for stimulating the immune response in some parts of the body.
“We found what we think are the inflammatory cells that drive fibrosis,” Kelly McNagny, professor of medical genetics, co-director of the UBC Biomedical Research Center and co-author of the study, said in a statement. “The gene that was defective in those cells is a hormone receptor, and there are drugs available that may be able to block that hormone receptor in normal cells and prevent fibrotic disease.”
|Read Full Article: New Discovery Could Aid Patients Suffering from Crohn’s Disease : News : Nature World News|