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Oral Psoriasis: Diagnosis and Treatment 

Psoriasis that affects the skin is common, but oral psoriasis is much less common.

Cutaneous psoriasis is frequently encountered in clinical practice, in contrast to oral psoriasis, which is considerably less common.1 A recent article by Fatahzadeh and Schwartz1reviews the diagnosis and management of this rare condition, which the authors describe as an “overlooked enigma.”

Why is Oral Psoriasis So Rarely Diagnosed?

The authors characterize the true incidence of oral involvement in psoriasis as “unknown” because few patients with psoriasis actually have their oral cavities carefully examined.2 One reason for this omission is that oral lesions are often asymptomatic, and therefore do not come to the clinician’s attention. The diagnosis, when it is made, is rarely confirmed histologically.3 Moreover, there is a more accelerated rate of epithelial turnover in cutaneous lesions than in oral lesions, so oral changes are “clinically subtle and difficult to recognize.”1

Perioral and Oral Manifestations of Psoriasis

There are several different locations in the perioral and oral areas that can be affected by psoriasis. Psoriatic involvement of the vermilion border is “rare,” according to the authors, and may occur with or without oral cavity involvement. Since the lips are partially keratinized, psoriasis affecting that region behaves similarly to cutaneous lesions, presenting with diffuse erythema, fissuring, silvery scales, and desquamation that starts from the commissures and spreads to involve both lips. It can be accompanied by bleeding, serious exudate, itching, and discomfort aggravated by mastication and lip movements.4 It is often confused with solar cheilosis, chronic eczema, actinic dermatitis, chronic candidiasis, or leukoplakia, leading to delayed diagnosis.4

Psoriasis usually affects the oral cavity in the buccal mucosa, with the palate and gingiva less frequently affected.3Morphological patterns include diffuse, intense mucosal erythema associated with acute psoriatic flares, well-defined, annual, white or grayish-yellow lesions, and mixed, ulcerative vesicular, pustular, and indurated entities.1Oral findings can be transient, migratory, and frequently fluctuating parallel to the exacerbation or remission of cutaneous lesions.1 There is a higher prevalence of benign migratory glossitis (BMG) and fissured tongue (FT) in psoriatic patients, compared to the general population.

Read Full Article: Oral Psoriasis: Diagnosis and Treatment – MPR

Read Full Article: Oral Psoriasis: Diagnosis and Treatment – MPR

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