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Ovarian reserve low in premenopausal women with psoriasis

Psoriasis in women can affect reproductive capability.

Women with psoriasis could have a harder time getting pregnant, according to new research.

Based on a study published in the Taiwanese Journal of Obstetrics & Gynecology, these patients have a diminished ovarian reserve or a number of follicles capable of producing a mature, healthy egg for fertilization.

Current data suggests female hormones released during pregnancy impact the course of psoriasis, and, at the same time, psoriasis affects pregnancy outcomes. However, no previous research exists into the ovarian reserve and function of psoriatic patients.

According to study authors, knowing how psoriasis might affect pregnancy chances can be very important for women interested in having a family.

“Average age of diagnosis in women with psoriasis is 28, a prime age for pregnancy,” the authors wrote. “Therefore, many female patients with psoriasis are concerned about adverse effects of the disease on their future fertility.”

Although age is a factor in determining whether a woman can get pregnant, it has limited usefulness in predicting individual ovarian performance. Consequently, knowing a woman’s ovarian reserve is increasingly important clinically.

And, the measure of a number of factors can help determine the quality of a woman’s ovarian reserve. These include basal follicle stimulating hormone (FSH), estrogen (E2), FSH/luteinizing hormone (LH) ratio, Inhibin B, and antimullerian hormone (AMH). Ovarian volume (OV) and antral follicle count (AFC) determine ovary size and shape.

Read on: Ovarian reserve low in premenopausal women with psoriasis | Dermatology Times

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