Pain and Mobility Are Major Problems for Patients with Hemophilia

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Pain and Mobility Are Major Problems for Patients with Hemophilia

Common complications from hemophilia include pain and mobility impairment, which are associated with uncontrolled bleeding. More than 60% of people with hemophilia report mobility problems and pain concerns.

New research further supports the understanding that patients with hemophilia suffer from pain and mobility issues, and it went on to uncover which joints are most greatly affected by the condition.

Christine Kempton, MD, MSc, from Emory University in Georgia, and colleagues used multiple strategies to find how big of an impact hemophilia has on pain and quality of life. Kempton presented the new research at the 57th American Society of Hematology Annual Meeting (ASH 2015) in Orlando, Florida.

The team evaluated 381 men with congenital hemophilia A or B with or without inhibitors with any severity. The patients had to be at least 18-years-old and the average age was 34. They underwent five patient-reported outcome (PRO) measures, as well as a hemophilia joint health score evaluation. Data was collected during routine clinical visits:

  • EQ-5D-SL with visual analog scale (VAS)
  • Modified Brief Pain Inventory v2 Short Form (BPI)
  • International Physical Activity Questionnaire (IPAQ)
  • SF-36v2 (functional health and well-being)
  • Haemophilia Activites List (HAL)

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