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Safety Bulletin: Pain Relievers and Liver Disease 

For those with chronic liver disease, it’s important to make the right choice about pain relievers.

For some people, relieving pain is as simple as taking a few over-the-counter pills. For those with liver disease, pain relief can be a bit more complicated. Just like the food we eat and the beverages we consume, any medications we ingest must be processed by the liver. Regrettably, liver disease can impair drug metabolism – potentially putting the liver in peril when taking pain-relieving medications.

The American Liver Foundation reported that 30 million Americans were living with chronic liver disease in 2010, or roughly 1 in 10 people. According to a 2011 Institute of Medicine Report from the Committee on Advancing Pain Research, Care, and Education, 100 million Americans live with chronic pain. When taken together, the number of people likely in pain (especially chronic pain) concurrent with chronic liver disease is staggering.

Typically, those with mild liver disease can safely take most common medications (prescription and non-prescription) at the recommended dose. Mild liver disease does not necessarily increase the risk that a given medication will be toxic to the liver. However, should a problem occur in someone with mild liver disease, the drug-induced liver damage would be more severe than it would be in an otherwise healthy person. Unfortunately, those with more advanced liver disease (such as cirrhosis), have a greater risk of drug-induced liver damage because the liver’s ability to metabolize medications is impaired.

Read Full Article: Safety Bulletin: Pain Relievers and Liver Disease |

Read Full Article: Safety Bulletin: Pain Relievers and Liver Disease |

The health and medical information on our website is not intended to take the place of advice or treatment from health care professionals. It is also not intended to substitute for the users’ relationships with their own health care/pharmaceutical providers.

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