Shifting Patterns of Hepatitis C Genotypes Distribution Seen

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Shifting Patterns of Hepatitis C Genotypes Distribution Seen

There are seven genotypes of hepatitis C.

Researchers have identified changes in the distribution of hepatitis C virus (HCV) genotypes in patients who also have human immunodeficiency virus (HIV) in a particular region of China. The movement in genotypes is described in a paper recently published on the web site PLOS One. The research was conducted by Weilie Chen, of the Department of Infectious Disease at Guangzhou No. 8 People’s Hospital in Guangzhou, China, and colleagues.

The most common cause of death in patients with HIV has become co-infection with HCV. The researchers say, “The distribution of HCV genotypes varies with geographical regions and time, and limited studies have focused on the HCV genotype in HIV/HCV co-infection.” In order to learn more about the distribution of the HCV genotypes, they examined data from 414 patients in three regions of China: South, Central, and Northwest.

“Seven HCV genotypes (1 to 7) and a large number of subtypes have been identified and are distributed worldwide,” say the authors. East Asia is the most common area to find genotype 1, 2, and 6. Genotype is important in the management of the disease, and though there have been indications that genotypes 1b and 2a are the most common in China, there is little data available regarding HIV/HCV co-infection specifically.

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