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Taste Sensory Deficit Underestimated in Multiple Sclerosis Patients

Multiple sclerosis can cause changes to the sense of taste; new research indicates that this problem is more widespread than previously thought.

Multiple sclerosis (MS) patients may exhibit taste sensory deficits more often than previously understood, according to findings published in the Journal of Neurology.

Researchers from the University of Pennsylvania School of Medicine gave patients a taste test in order to build a detailed assessment of whether taste function is related to brain lesions found in the central nervous system of MS patients. The taste test used sweet (sucrose), sour (citric acid), bitter (caffeine) and salty (NaCl) samples in 73 MS patients and 73 control subjects, who then underwent MRI testing to search for brain lesions in 52 brain regions.

The MS patients scored significantly lower than their non MS counterparts among all four taste groups in both the anterior and posterior tongue regions, the researchers reported. Between 15 and 32 percent of the MS patients had taste scores below the fifth percentile of the control patients: caffeine, 15.07 percent; citric acid, 21.9 percent; sucrose, 24.66 percent; and NaCl, 31.5 percent. These numbers are about twice as high as previous studies’ conclusions into this topic – between five and 20 percent.

The researchers said that the taste scores were linked to the number and volume of brain legions on the frontal and temporal lobes. MRIs showed that taste scores were inversely correlated with lesion volumes in the temporal, medial frontal and superior frontal loves. Additionally, the taste scores were correlated to the number of lesions in the left and right superior frontal lobes, right anterior cingulated gyrus and left parietal operculum.

Read Full Article: Taste Sensory Deficit Underestimated in Multiple Sclerosis Patients

 

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