A key protein might trigger a damaging interaction in multiple sclerosis.
Using tissue samples from the brains of deceased MS patients, the researchers identified a key protein that seems to set in motion a damaging interaction that ultimately leads to “cellular suicide.”
“The finding, and this is a very novel finding, of our study is that this protein is highly upregulated in MS brains,” said Thomas Simmen, a cell biology professor who served as co-author of the research.
“Two aspects of the MS phenotype get boosted by having too much of this protein. One is that you have … brain cells undergoing unwanted cell death. And secondly, it will also boost inflammation.”
|Read Full Article: University of Alberta study sheds light on defect behind multiple sclerosis | Edmonton Journal|