When obese patients with psoriasis experience weight loss after bariatric surgery, there is a tendency for the psoriasis or psoriatic arthritis to also improve.
Obese patients with psoriasis or psoriatic arthritis reported clinical improvements following the dramatic weight loss associated with bariatric surgery, a researcher reported here.
At 1 year after bariatric surgery, patients with psoriasis had a decrease in patient-reported disease severity ratings from 5.6 out of 10 to 4.4, which subsequently fell further to 3.3 at their most recent follow-up visit, according to Soumya M. Reddy, MD, of New York University in New York City.
Among those with psoriatic arthritis, the baseline severity rating was 6.4, which decreased to 4.5 at 1 year and 3.9 at their most recent visit, Reddy reported in a press conference at the annual meeting of the American College of Rheumatology.
Obesity is known to be more common among patients with psoriasis and psoriatic arthritis compared with the general population, an association that is likely to originate in fat tissue-driven systemic inflammation.
Small case series have suggested that patients with psoriasis and psoriatic arthritis may experience improvements after weight loss, but the effects of surgical weight loss are unclear.
To examine this, she and her colleagues reviewed the medical charts of 9,073 patients who underwent bariatric surgery from 2002 to 2013, identifying 86 who had been diagnosed with psoriasis before the procedure. Among that group, 21 had been diagnosed with psoriatic arthritis.
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