When Gene Tests for Breast Cancer Reveal Grim Data but No Guidance

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When Gene Tests for Breast Cancer Reveal Grim Data but No Guidance

Some patients who undergo genetic testing about cancer risk are left with frightening information but no clear guidance on how to fight the disease.

At a time when genetic testing and genetically personalized treatments for cancer are proliferating, buoyed by new resources like President Obama’s $215 million personalized medicine initiative, women with breast cancer are facing a frustrating reality: The genetic data is there, but in many cases, doctors do not know what to do with it.

That was the situation Angie Watts, 44, faced after she walked into a radiation oncologist’s office last June expecting to discuss the radiation therapy she was about to begin after a lumpectomy for breast cancer. Instead, Dr. Timothy M. Zagar of the University of North Carolina looked down at a sheet of test results and delivered some shocking news.

A genetic test showed she had inherited an alteration in a gene needed to repair DNA. Radiation breaks DNA, so the treatment might actually spur the growth of her cancer, he said. He urged her not to take the risk and to have a double mastectomy instead.

Read Full Article: When Gene Tests for Breast Cancer Reveal Grim Data but No Guidance – The New York Times

 

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